Thy1 promoter expression
Webb11 okt. 2024 · We generated multiple transgenic mouse lines with stable and reproducible expression of jRGECO1a under the Thy1 promoter (‘Thy1-jRGECO1a’ lines). Each line has … Webb18 okt. 2012 · To generate GCaMP transgenic mice, we used the well-characterized Thy1 promoter to express GCaMPs in neurons. We generated eight founder lines of GCaMP2.2c and six founder lines of GCaMP3. Our previous studies have shown that the Thy1 promoter predominantly drives transgene expression in projection neurons in the CNS.
Thy1 promoter expression
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WebbEleven Thy1-Cre lines exhibited transgene expression in several regions of the central and peripheral nervous systems, including the cerebral cortex, cerebellum, spinal cord, retina, and dorsal root ganglion. Thy1-Cre expression also resulted in region-specific activation of Cre reporter transgenes. Webb24 sep. 2014 · Thy1 transgenics can exhibit transgene expression in specific subsets of cortical projection neurons . In GP5.3 mice L2, but not L3 cells, were labeled over large parts of the cortex; in the neocortex of …
Webb9 apr. 2024 · Thy1 is a novel lymphatic vessel expressed gene, and has a potential role in the cell adhesion processes required for tumor progression and inflammation Findings suggest that Thy-1 down-regulates TNF-alpha-activated gene expression via interfering with SFK- and NF-kappaB-mediated transactivation. WebbThy-1 is highly expressed in ovarian cancer cells, especially serous adenocarcinoma. Bioinformatic analysis of ovarian tissue databases demonstrated higher expression of Thy-1 in cancerous versus...
Webb6 mars 2015 · In summary, we have characterized the sensory nerve expression of YFP in the Thy1.2 YFP-16 mouse. Contrary to previous reports, we have found that only certain TRPV1-negative neurons … Thy1 expression comes on when endothelial cells are activated. It has been shown to interact with the leukocyte integrin Mac1 (CD11b/CD18) and may play a role in leukocyte homing and recruitment. Modulating fibrosis. Role of Thy-1 in fibrosis and fibroblast differention may have some tissue variation. Visa mer Thy-1 or CD90 (Cluster of Differentiation 90) is a 25–37 kDa heavily N-glycosylated, glycophosphatidylinositol (GPI) anchored conserved cell surface protein with a single V-like immunoglobulin domain, originally discovered as a Visa mer The antigen Thy-1 was the first T cell marker to be identified. Thy-1 was discovered by Reif and Allen in 1964 during a search for … Visa mer The 25-kDa core protein (excluding the heavy glycosylation) of rodent Thy-1 is 111 or 112 amino acids in length, and is N-glycosylated at three sites (In contrast to only two glycosylation sites for human Thy-1). The 162aa (murine, 161 for human) Thy1 … Visa mer Thy1 expression varies between species. Amongst the cells reported to generally express Thy-1 are thymocytes (precursor of T cells in the thymus) & CD34(+) prothymocytes; Visa mer Thy-1 has been conserved throughout vertebrate evolution and even in some invertebrates, with homologs described in many species like squid, frogs, chickens, mice, rats, dogs, and humans. The Thy-1 gene is located at human chromosome 11q22.3 … Visa mer Thy-1 is one of the most heavily glycosylated membrane proteins with a carbohydrate content up to 30% of its molecular mass. Thy1 in most species has 3 N-glycosylation … Visa mer As a GPI-anchored protein, Thy-1 is present in the outer leaflet of lipid rafts in the cell membrane. In case of neurons it is known to be expressed strongly in the mature axon. The Visa mer
Webb1 okt. 2000 · Thy1 is an immunoglobulin superfamily member that is expressed by projection neurons in many parts of the nervous system, as well as by several …
Webb15 jan. 1995 · The transgenic Thy1.1 RNA can be distinguished from the endogenous Thy1.2 RNA. which is slightly greater in size. Although we could detect no Thyl mRNA in peritoneal macrophages from nontransgenic littermates (Fig 4 A, lane 1), a very high level of expression was observed in the CD11b/Thy1.1 animal (Fig 4 A, lane 2). tci sni2Webb21 mars 2024 · THY1 (Thy-1 Cell Surface Antigen) is a Protein Coding gene. Diseases associated with THY1 include Retinal Artery Occlusion and Thymoma . Among its … tci satnaWebbNeocortical expression levels in Thy1- GCaMP6 mice are 2–10 fold lower than typical conditions of AAV infection (Fig. 3). Since AAV infection produces [GCaMP] of … tci sds検索Webb8 aug. 2024 · As reported, Thy1 expression coupled with the established T cell gene, ... back-to-back Thy1 promoters were used in order to drive both CreERT2 and to specifically label neurons with EYFP. tci skinWebbTissue expression cluster i The RNA data was used to cluster genes according to their expression across tissues. Clusters contain genes that have similar expression patterns, … bateria nokia 5110Webb11 apr. 2002 · Eleven Thy1-Cre lines exhibited transgene expression in several regions of the central and peripheral nervous systems, including the cerebral cortex, cerebellum, … bateria nokia 6120iWebbExpression of THY1 (CD90) in ovary tissue. Antibody staining with HPA003733, CAB068243 and CAB068244 in immunohistochemistry. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again. THY1. SECTIONS. bateria nokia 6100