Protein kinase c alpha type
WebA St-Denis, et al. Protein kinase C-alpha modulates lipopolysaccharide-induced functions in a murine macrophage cell line. J Biol Chem. 1998 Dec 4;273(49):32787-92. [Content …
Protein kinase c alpha type
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WebFeb 7, 2011 · 672. Molecular Weight. 76749.445. Theoretical pI. 7.05. GO Classification. Functions. ATP binding / calcium-dependent protein kinase C activity / enzyme binding / … WebThe protein kinase fold consists of an N-terminal lobe, which is formed by five beta sheet strands and one alpha helix called the C-helix, ... Kincore provides conformational assignments and ligand type labels to protein kinase structures from the PDB. As of April 2024, it contains structures from 278 kinase genes (284 domains) ...
WebLegend. Protein kinase C (PKC) family members regulate numerous cellular responses including gene expression, protein secretion, cell proliferation, and the inflammatory … WebALPK3 ENSG00000136383 alpha-kinase 3 ... ATP10A ENSG00000206190 ATPase, class V, type 10A BIRC3 ENSG00000023445 baculoviral IAP repeat containing 3 ... PRKCE …
WebUniProt website fallback message If you are not seeing anything on this page, it might be for multiple reasons: You might have JavaScript disabled: make sure to ... Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca 2+ handling in myocytes. Protein kinase C-alpha (PKC-α) is a specific member of the protein kinase family. These enzymes are characterized by their ability to add a phosphate group to other … See more Protein kinase C alpha (PKCα) is an enzyme that in humans is encoded by the PRKCA gene. See more Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in … See more Using infrared spectroscopy techniques, researchers have demonstrated that the secondary structure of PKC alpha consists of around 44% beta sheets and nearly 22% alpha helices … See more Increased activation of PKCα is associated with the growth and invasion of cancers. High levels of PKCα are linked to malignant brain cancer. … See more PKC-α is unique in its mode of regulation compared to other kinases within this family. In general, the protein kinase family is regulated by allosteric regulation, the binding of a … See more Epithelium Another field of research has indicated that PKC-α plays a vital role in epithelial tissue, the tissue that covers all external and internal surfaces of the body. Specifically, PKC-α is involved in altering the function of See more PKC alpha has been shown to interact with: • C1QBP, • CD29, • EGFR, See more
WebProtein kinase C alpha type. Gene. PRKCA. Source organism. Bos taurus (Bovine) go to search. UniProt. P04409 ... in the PDB. Biological function. Calcium-activated, …
WebAug 28, 2008 · Stakkestad Ø, Larsen A, Kvissel A, Eikvar S, Ørstavik S and Skålhegg B (2011) Protein kinase A type I activates a CRE-element more efficiently than protein kinase A type II regardless of C subunit isoform, BMC Biochemistry, 10.1186/1471-2091-12-7, 12:1, Online publication date: 1-Dec-2011. horsley drive gorlestonWebProteins. Immune Checkpoint; Coronavirus Antigens; SARS-CoV-2 Antigens; Ubiquitination related reagent; CAR-T Cell Therapy Targets; Fc & Fc Receptor; Bio-Markers & CD Antigens; Interleukin; TNF Family; Cytokines & Cytokine Receptors; Growth Factor; Cell Culture Related; Biosimilar Drug Targets; Tool proteins; Other Recombinant Protein; … horsley ear clinicWebProtein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family … pst. files in windows 10WebProtein kinase C does not have any known nuclear localization signal but, nevertheless, is redistributed from the cytoplasm to the nucleus upon various stimuli. In NIH 3T3 … pst422fcwzr1rWebALPK3 ENSG00000136383 alpha-kinase 3 ... ATP10A ENSG00000206190 ATPase, class V, type 10A BIRC3 ENSG00000023445 baculoviral IAP repeat containing 3 ... PRKCE ENSG00000171132 protein kinase C, epsilon RAB20 ENSG00000139832 RAB20, member RAS oncogene family pst4021cws81uWebSep 2, 2009 · Primary Citation of Related Structures: 3IW4. PubMed Abstract: A series of novel maleimide-based inhibitors of protein kinase C (PKC) were designed, … horsley drive smithfieldWeb(RefSeq) LOW QUALITY PROTEIN: protein kinase C alpha type. KO: K02677 : classical protein kinase C alpha type [EC:2.7.11.13] Organism: plop Perognathus longimembris pacificus (Pacific pocket mouse) Pathway: plop01521 : EGFR tyrosine kinase inhibitor resistance: plop04010 : MAPK signaling pathway: plop04012 : horsley electrical shop