2024 Lamp1蛋白与自噬

Lamp1蛋白与自噬

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August undefined, 2024

Tīmeklis参与成熟阶段的溶酶体相关蛋白还包括： LAMP1、 LAMP2、 UVRAG (紫外线抵抗相关肿瘤抑制基因)。 5）自噬体的裂解阶段：是指自噬溶酶体膜的裂解及内容物在溶酶 … Tīmeklislamp1 蛋白羧基末端暴露在细胞浆中，同时它含有一个将 lamp 蛋白靶向至溶酶体膜的酪氨酸分类基序 (4)。lamp1 和 lamp2 的蛋白序列有 37% 同源性。lamp1 和 lamp2 均 …

Characterization of LAMP1-labeled nondegradative lysosomal and …

TīmeklisLAMP1（溶酶体相关膜蛋白1）和LAMP2分布在自噬和溶酶体细胞器中。尽管分布广泛，但LAMP1通常用作溶酶体标记物，而LAMP1阳性细胞器通常称为溶酶体区室。 … Tīmeklis2008. gada 23. sept. · LAMP1 DMDM 206729915 ClinGen HGNC:6499 GenCC HGNC:6499 PTM/Processing Features Showing features for signal, chain, glycosylation, disulfide bond. Expand table Post-translational modification O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans. The glycosylation of N … bird face emoticon

细胞器标志物丨LAMP1抗体 - 知乎 - 知乎专栏

TīmeklisKey features and details Rabbit polyclonal to LAMP1 - Lysosome Marker Suitable for: IHC-P, WB Reacts with: Human Isotype: IgG 选择批间可重复性更高的重组抗体 Anti-LAMP1 antibody [EPR4204] - Lysosome Marker (ab108597) 研究可靠 —— 各批次间结果一致且可重复长期批量供应 —— 采用重组技术，可实现快速生产首次实验即可 … Tīmeklis摘要. LAMP1 antibody detects lysosome-associated membrane protein 1 (LAMP-1, or CD107a), a transmembrane glycoprotein that generally migrates at ~120 kDa on western blot. LAMP1 and LAMP2 are major protein components of lysosomal membranes, though both proteins appear to have a more dynamic distribution that … TīmeklisLAMP1. Lysosomal-associated membrane protein 1 ( LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a ( C luster of D ifferentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, band 4 (13q34). dalvin cook changes number to 4

Different localization of lysosomal-associated membrane protein 1 ...

TīmeklisAnti-LAMP1 antibody - Lysosome Marker (ab24170) at 1/700 dilution (in 5% milk for 4 hours at 20°C) + Rat Kidney - whole tissue lysate at 18 µg Secondary An HRP … Tīmeklis2024. gada 28. jūl. · 1、自噬，就是细胞自己吃掉自己，废物再利用的代谢过程； 2、在正常情况下，自噬维持细胞内稳态； 3、在外界压力、饥饿、缺氧和内质网应激等特 … dalvin cook contractTīmeklisPA1-654A detects Lamp1 from human samples. PA1-654A has been successfully used in immunofluorescence and Western blotting procedures. In immunofluorescence procedures, this antibody stains Lamp1 in HeLa cells resulting in perinuclear staining. The PA1-654A immunogen is a synthetic peptide corresponding to residues C K … bird face meme

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Lamp1蛋白与自噬

LAMP1 (D2D11) XP® Rabbit mAb Cell Signaling Technology

Tīmeklis2024. gada 12. okt. · lamp1是溶酶体膜蛋白，在溶酶体外泌过程中随着溶酶体膜与细胞膜融合而定位于细胞膜表面【7,8】。该研究发现，与对照细胞相比，细胞质膜定位 … TīmeklisLAMP1 蛋白羧基末端暴露在细胞浆中，同时它含有一个将 LAMP 蛋白靶向至溶酶体膜的酪氨酸分类基序 (4)。 LAMP1 和 LAMP2 的蛋白序列有 37% 同源性。 LAMP1 和 …

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TīmeklisLysosome-associated membrane protein-2 (LAMP-2)はリソソームを形成する膜に豊富に存在する、高度に糖鎖付加されたタンパク質です。. 発見当初LAMP-2の役割は ... Tīmeklis2024. gada 3. sept. · Despite widespread distribution of LAMP1 and the heterogeneous nature of LAMP1-labeled compartments, LAMP1 is routinely used as a lysosomal marker, and LAMP1-positive organelles are often referred to as lysosomes. In this study, we use immunoelectron microscopy and confocal imaging to provide quanti …

Tīmeklis2024. gada 30. marts · Present results indicate that prolonged treatment with SUN affects LAMP1 and LAMP2 expression only marginally in most patients. In contrast, changes in ATP6V1B2 expression were marked and resembled irregular oscillations. Very similar changes in the expression of lysosomal membrane proteins were also … TīmeklisLAMP1 - lysosomal associated membrane protein 1 Gene 基因蛋白疾病直系同源中文名称：溶酶体相关膜蛋白 1 种属: Homo sapiens 同用名: LAMPA; CD107a; LGP120 …

Tīmeklis2024. gada 6. janv. · LAMP1 possesses a large luminal ectodomain and transmembrane domain, followed by a short C-terminal cytoplasmic tail (Fukuda 1991; Eskelinen et al. 2003 ). LAMP1 has a molecular mass of between 90 and 120 kDa, and is heavily glycosylated with a large number of N-glycans and some O-glycans (Fukuda 1991; … Tīmeklis2024. gada 23. janv. · 4）自噬体的成熟阶段：自噬体的成熟主要是指自噬体通过微管骨架在转运必须内吞体分类复合物(escrt)和单体 gtp 酶(rab s)作用下，与溶酶体融合形成自噬溶酶体的过程。参与成熟阶段的溶酶体相关蛋白还包括：lamp1、 lamp2、 uvrag(紫外线抵抗相关肿瘤抑制基因)。

Tīmeklis2024. gada 17. janv. · We corroborated that the perinuclear clustering of late endocytic organelles containing Lamp1 (lysosome-associated membrane protein 1) is reduced in BLOC-3-deficient murine fibroblasts. Utilizing Tandem MS (MS/MS) sequencing, we report the novel finding of the 95 kDa murine transmembrane protein, LAMP-1, …

Tīmeklis2024. gada 27. jūl. · 在肿瘤转移过程中，LAMP1能作为microRNA抑制自噬并发挥抗肿瘤作用的直接靶点，其可通过引起溶酶体功能障碍并影响溶酶体水解酶的表达及活性发 … dalvin cook draft yearTīmeklisTo investigate its role during EAE, we inactivated Lamp1 in astrocytes using a lentivirus that co-expresses Gfap-driven CRISPR–Cas9 and either a Lamp1-targeting or a non-targeting single-guide ... bird face feathersTīmeklis2013. gada 6. jūn. · LAMP1 is important for perforin trafficking to the lytic granules and granule movement. Abstract Secretory lysosomes of natural killer (NK) cells, containing perforin and granzymes, are indispensable for NK-cell cytotoxicity because their release results in the induction of target-cell apoptosis. bird face paintingTīmeklis2024. gada 15. dec. · 自噬体与溶酶体的直接融合形成自噬溶酶体，形成过程中主要是 LAMP1、Rab7、UVRAG 和 Rubicon 的参与。降解及再循环利用 ATG9 作为唯一 … bird facing forwardTīmeklis2005. gada 15. nov. · High levels of LAMP1-GFP overexpression elicited aberrant aggregation of late endocytic organelles, a phenomenon that probably involved formation of anti-parallel dimers of LAMP1-GFP as it was not observed in cells expressing comparable levels of a non-dimerizing mutant variant, LAMP1-mGFP. To … dalvin cook familyTīmeklisLysosomal-associated membrane protein 1 (LAMP1) mainly localizes to lysosomes and late endosomes. We herein investigated the intracellular localization of lysosomal membrane proteins in five mammalian cultured cell lines. Rat LAMP1 fused to enhanced green fluorescent protein (EGFP) mostly accumulate … bird facing rightTīmeklis溶酶体相关膜蛋白LAMP1 (lysosome-associated membrane protein 1)是主要存在于溶酶体膜上的一种高度糖基化的糖蛋白,参与细胞内多种生理和病理过程.近年有关LAMP1 … bird facing front