http://mdedge.ma1.medscape.com/obgyn/article/50241/obstetrics/des-exposure-elevates-risk-12-adverse-outcomes WebNov 1, 2011 · In-utero exposure to diethylstilbestrol was associated with a high lifetime risk of a broad spectrum of adverse outcomes in a follow-up study of patients now in their 40s, 50s, and 60s. Most of these risks were increased by a factor of more than two, compared with the risks in women of the same age who were not exposed to diethylstilbestrol ...
Diethylstilbestrol - an overview ScienceDirect Topics
WebMar 7, 2024 · Last Reviewed: March 7, 2024 Diethylstilbestrol (DES) was the first synthetic (manmade) estrogen. It was given to pregnant women from 1938-1971. It was thought to prevent miscarriages and promote "healthy pregnancies." Webwere exposed to diethylstilbestrol(DES) in utero (when they were in their mother’s womb). See Risk Factors for Vaginal Cancer2€for more information on DES and clear cell … rain taxi
Evidence of intergenerational transmission of diethylstilbestrol …
WebAug 27, 2024 · J Toxicol Environ Health. 1976;1(4):587–605. Article CAS Google Scholar Saeed M, Rogan E, Cavalieri E. Mechanism of metabolic activation and DNA adduct formation by the human carcinogen diethylstilbestrol: the defining link to natural estrogens. Int J Cancer. 2009;124(6):1276–84. WebDiethylstilbestrol is no longer commercially available in the USA (McEvoy, 2007). 1.2.3 Trends in use Most reports about diethylstilbestrol use are from the USA. The number of women exposed prenatally to diethylstilbestrol worldwide is unknown. An estimated 5 to 10 million US citizens received diethylstilbestrol during preg- WebJul 17, 2024 · A multi-use artificial hormone, Diethylstilbestrol was controversial from its discovery, with the inventor of the drug warning of possible side effects. Its impact on users, and their children, is still felt today. Diethylstilbestrol (DES) was one of the first artificial female hormones to be synthesised in the laboratory. hawkestone ontario map